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Gene Review:

sox11 - SRY (sex determining region Y)-box 11

Xenopus (Silurana) tropicalis

Synonyms: XLS13, XLS13b, xSOX-11, xls13a, xsox11

de Martino, S. et al., Hargrave, M. et al.

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High impact information on sox11

Expression of sox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development [1].
Thus, the zebrafish duplicate genes appear to have reciprocally lost expression domains present in the sox11 gene of the last common ancestor of tetrapods and zebrafish [1].
In addition to an N-terminal HMG box domain, the deduced SOX11 protein contains a number of highly conserved C-terminal motifs, which may function in transcriptional regulation [2].

References

Expression of sox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development. de Martino, S., Yan, Y.L., Jowett, T., Postlethwait, J.H., Varga, Z.M., Ashworth, A., Austin, C.A. Dev. Dyn. (2000) [Pubmed]
Expression of the Sox11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Hargrave, M., Wright, E., Kun, J., Emery, J., Cooper, L., Koopman, P. Dev. Dyn. (1997) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

sox11a	Danio rerio
SOX11	Gallus gallus
SOX11	Homo sapiens
SOX11	Macaca mulatta
Sox11	Mus musculus
SOX11	Pan troglodytes
Sox11	Rattus norvegicus

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