Gene Review:
PTGES3 - prostaglandin E synthase 3 (cytosolic)
Bos taurus
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High impact information on CPGES
- The present study was undertaken to clone bovine MPGES2 and CPGES and to report on their regulation in the endometrium during the estrous cycle [1].
- In addition, using the bovine endometrial cell line BEND, where higher accumulation of PGE(2) is observed following treatment with phorbol 12-myristate 13-actetate (PMA) and tumor necrosis factor-alpha (TNF-alpha), we have found an associated increase of MPGES1 and COX2 but not CPGES or MPGES2 protein expression [1].
References
- Expression and contribution of three different isoforms of prostaglandin E synthase in the bovine endometrium. Parent, J., Fortier, M.A. Biol. Reprod. (2005) [Pubmed]
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