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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RNF141  -  ring finger protein 141

Homo sapiens

Synonyms: RING finger protein 141, ZFP26, ZNF230, Zinc finger protein 230
 
 
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High impact information on RNF141

 

Biological context of RNF141

  • Therefore, it is postulated that znf230 may function as a testis specific transcription factor during mouse spermatogenesis [2].
 

Analytical, diagnostic and therapeutic context of RNF141

  • The lack of detectable ZNF230 expression in azoospermic patients by reverse transcriptase-mediated PCR analysis is interpreted to mean that this gene is involved in maintaining normal human male fertility [1].

References

  1. The shorter zinc finger protein ZNF230 gene message is transcribed in fertile male testes and may be related to human spermatogenesis. Zhang, S., Qiu, W., Wu, H., Zhang, G., Huang, M., Xiao, C., Yang, J., Kamp, C., Huang, X., Huellen, K., Yue, Y., Pan, A., Lebo, R., Milunsky, A., Vogt, P.H. Biochem. J. (2001) [Pubmed]
  2. Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230. Qiu, W., Zhang, S., Xiao, C., Xu, W., Ma, Y., Liu, Y., Wu, Q. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
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