Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

GLRX3 - glutaredoxin 3

Bos taurus

Synonyms: PICOT, TXNL2

Chen, W.J. et al., Quéméneur, E. et al., Lundström, J. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on TXNL2

Phosphoamino acid analysis and cyanogen bromide cleavage indicate that the modification site lies on a threonine residue within the central region of the protein outside the thioredoxin-like domains [1].
Protein disulfide-isomerase (PDI) contains two thioredoxin-like domains with the active-site sequence: Cys-Gly-His-Cys [2].
Owing to the structure-based sequence alignment revealing homology between the "nonessential" disulfide of bpDNase and the active-site motif of thioredoxin, we measured 39% of the thioredoxin-like activity for bpDNase based on the rate of insulin precipitation (DeltaA650nm/min) [3].

References

A major phosphoprotein of the endoplasmic reticulum is protein disulfide isomerase. Quéméneur, E., Guthapfel, R., Gueguen, P. J. Biol. Chem. (1994) [Pubmed]
Determination of the reduction-oxidation potential of the thioredoxin-like domains of protein disulfide-isomerase from the equilibrium with glutathione and thioredoxin. Lundström, J., Holmgren, A. Biochemistry (1993) [Pubmed]
Biological functions of the disulfides in bovine pancreatic deoxyribonuclease. Chen, W.J., Lee, I.S., Chen, C.Y., Liao, T.H. Protein Sci. (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AT4G04950	Arabidopsis thaliana
AGOS_AGR111W	Ashbya gossypii ATCC 10895
glrx-3	Caenorhabditis elegans
GLRX3	Canis lupus familiaris
glrx3	Danio rerio
GLRX3	Gallus gallus
GLRX3	Homo sapiens
KLLA0C17842g	Kluyveromyces lactis NRRL Y-1140
GLRX3	Macaca mulatta
MGG_06356	Magnaporthe oryzae 70-15
Glrx3	Mus musculus
NCU09803	Neurospora crassa OR74A
Os10g0500700	Oryza sativa Japonica Group
GLRX3	Pan troglodytes
Glrx3	Rattus norvegicus
GRX4	Saccharomyces cerevisiae S288c
GRX3	Saccharomyces cerevisiae S288c
grx4	Schizosaccharomyces pombe 972h-
glrx3	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share