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Gene Review

GLRX3  -  glutaredoxin 3

Homo sapiens

Synonyms: GLRX4, GRX3, GRX4, Glutaredoxin-3, HUSSY-22, ...
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Disease relevance of TXNL2


High impact information on TXNL2


Associations of TXNL2 with chemical compounds

  • The X-ray crystal structures of PGHS-1 in complex with the NSAIDs flurbiprofen and bromoaspirin have been determined previously [Picot, D., et al. (1994) Nature 367, 243-249; Loll, P. J., et al. (1995) Nat. Struct. Biol. 2, 637-643] [7].


  1. Containing hypertrophy with a PICOT fence. Dorn, G.W. Circ. Res. (2006) [Pubmed]
  2. Evidence-based assessment: evaluation of the formocresol versus ferric sulfate primary molar pulpotomy. Loh, A., O'Hoy, P., Tran, X., Charles, R., Hughes, A., Kubo, K., Messer, L.B. Pediatric dentistry. (2004) [Pubmed]
  3. Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme. Sadek, C.M., Jiménez, A., Damdimopoulos, A.E., Kieselbach, T., Nord, M., Gustafsson, J.A., Spyrou, G., Davis, E.C., Oko, R., van der Hoorn, F.A., Miranda-Vizuete, A. J. Biol. Chem. (2003) [Pubmed]
  4. Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain. Witte, S., Villalba, M., Bi, K., Liu, Y., Isakov, N., Altman, A. J. Biol. Chem. (2000) [Pubmed]
  5. Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety. Mancini, J.A., Riendeau, D., Falgueyret, J.P., Vickers, P.J., O'Neill, G.P. J. Biol. Chem. (1995) [Pubmed]
  6. Tyrosine phosphorylation of PICOT and its translocation to the nucleus in response of human T cells to oxidative stress. Babichev, Y., Isakov, N. Adv. Exp. Med. Biol. (2001) [Pubmed]
  7. Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site. Loll, P.J., Picot, D., Ekabo, O., Garavito, R.M. Biochemistry (1996) [Pubmed]
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