High impact information on PRKAG3

• Northern blot analysis demonstrated that, similar to other species, the bovine PRKAG3 transcript was only expressed in skeletal muscle [1].
• The bovine PRKAG3 gene comprises 13 exons and spans approximately 6.8 kb on BTA2 [1].
• Molecular cloning and characterization of bovine PRKAG3 gene: structure, expression and single nucleotide polymorphism detection [1].
• The protein kinase adenosine monophosphate-activated gamma3-subunit (PRKAG3) gene encodes a muscle-specific isoform of the regulatory gamma-subunit of adenosine monophosphate-activated protein kinase, which plays a key role in regulating energy homeostasis in eucaryotes [1].

Anatomical context of PRKAG3

• It is well known that mutations in the PRKAG3 gene affect high glycogen content in the porcine skeletal muscle and, consequently, meat quality [1].

References