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Gene Review

Prkag3  -  protein kinase, AMP-activated, gamma 3 non...

Mus musculus

Synonyms: 5'-AMP-activated protein kinase subunit gamma-3, AMPK gamma3, AMPK subunit gamma-3, AMPKg3, AMPKg3L, ...
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High impact information on Prkag3


Analytical, diagnostic and therapeutic context of Prkag3

  • We used AMPK3 transgenic (Tg-Prkag3225Q) and knockout (Prkag3-/-) mice to determine the relationship between AMPK activity, glycogen content, and ergogenics (ability to perform work) in isolated extensor digitorum longus skeletal muscle after contractions induced by electrical stimulation [4].


  1. Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice. Nilsson, E.C., Long, Y.C., Martinsson, S., Glund, S., Garcia-Roves, P., Svensson, L.T., Andersson, L., Zierath, J.R., Mahlapuu, M. J. Biol. Chem. (2006) [Pubmed]
  2. Changes in Exercise-Induced Gene Expression in 5'-AMP-Activated Protein Kinase {gamma}3-Null and {gamma}3 R225Q Transgenic Mice. Barnes, B.R., Long, Y.C., Steiler, T.L., Leng, Y., Galuska, D., Wojtaszewski, J.F., Andersson, L., Zierath, J.R. Diabetes (2005) [Pubmed]
  3. Role of AMP--activated protein kinase in the control of glucose homeostasis. Barnes, B.R., Zierath, J.R. Curr. Mol. Med. (2005) [Pubmed]
  4. 5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics. Barnes, B.R., Glund, S., Long, Y.C., Hjälm, G., Andersson, L., Zierath, J.R. FASEB J. (2005) [Pubmed]
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