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Gene Review

PIN1P1  -  peptidylprolyl cis/trans isomerase, NIMA...

Homo sapiens

Synonyms: PIN1L, Peptidylprolyl cis-trans isomerase NIMA-interacting 1 pseudogene 1
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High impact information on PIN1L

  • As part of this study, we isolated the putative polar auxin transport genes, PttLAX1-PttLAX3 and PttPIN1-PttPIN3, belonging to the AUX1-like family of influx and PIN1-like efflux carriers, respectively [1].
  • Primers were designed to discriminate between the two transcripts, and PCR on DNA from hamster/human somatic cell hybrids retaining chromosomes 1 or 19 was used to map the human PIN1 gene to chromosome 19, and PIN1L, a closely related gene, to chromosome 1 [2].
  • The protein encoded by PIN1L may have some functional role or alternatively PIN1L may be a transcribed pseudogene [2].

Biological context of PIN1L


Analytical, diagnostic and therapeutic context of PIN1L


  1. Polar auxin transport in the wood-forming tissues of hybrid aspen is under simultaneous control of developmental and environmental signals. Schrader, J., Baba, K., May, S.T., Palme, K., Bennett, M., Bhalerao, R.P., Sandberg, G. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  2. The human PIN1 peptidyl-prolyl cis/trans isomerase gene maps to human chromosome 19p13 and the closely related PIN1L gene to 1p31. Campbell, H.D., Webb, G.C., Fountain, S., Young, I.G. Genomics (1997) [Pubmed]
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