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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Nub1  -  negative regulator of ubiquitin-like...

Mus musculus

Synonyms: 4931404D21Rik, 6330412F12Rik, BS4, NEDD8 ultimate buster 1, NY-REN-18, ...
 
 
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Disease relevance of Nub1

 

High impact information on Nub1

  • The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1 [2].
  • The NUB1 message is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues and is developmentally down-regulated in mouse embryos [3].

References

  1. A determinant of resistance of Neisseria gonorrhoeae to killing by human phagocytes: an outer membrane lipoprotein of about 20 kDa with a high content of glutamic acid. Parsons, N.J., Kwaasi, A.A., Patel, P.V., Nairn, C.A., Smith, H. J. Gen. Microbiol. (1986) [Pubmed]
  2. The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1. Akey, D.T., Zhu, X., Dyer, M., Li, A., Sorensen, A., Blackshaw, S., Fukuda-Kamitani, T., Daiger, S.P., Craft, C.M., Kamitani, T., Sohocki, M.M. Hum. Mol. Genet. (2002) [Pubmed]
  3. NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression. Kito, K., Yeh, E.T., Kamitani, T. J. Biol. Chem. (2001) [Pubmed]
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