The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

CT45A1  -  cancer/testis antigen family 45, member A1

Homo sapiens

Synonyms: CT45, CT45-1, CT45.1, Cancer/testis antigen 45-1, Cancer/testis antigen 45A1, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of CT45-1

 

High impact information on CT45-1

  • Demethylation of CT45-negative HeLa cells and stimulated peripheral blood lymphocytes induced CT45 expression [2].
  • RESULTS: Immunopurification of the 25/22-kDa antigen and sequencing revealed a peptide of 14 amino acids corresponding to the gene product of the newly described gene family MGC27005, located on chromosome Xq26.3, now termed CT45 [2].
  • CT45 is significantly phosphorylated and down-regulated during mitosis [2].
 

Analytical, diagnostic and therapeutic context of CT45-1

  • The mean regurgitant orifice area at CT-45 mm(2) +/- 34 (range, 10-148 mm(2))-correlated significantly with the results at transesophageal echocardiography (r = 0.807, P < .001) and ventriculography (r = 0.922, P < .001) [3].

References

  1. Identification of cancer/testis-antigen genes by massively parallel signature sequencing. Chen, Y.T., Scanlan, M.J., Venditti, C.A., Chua, R., Theiler, G., Stevenson, B.J., Iseli, C., Gure, A.O., Vasicek, T., Strausberg, R.L., Jongeneel, C.V., Old, L.J., Simpson, A.J. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  2. Characterization and expression of CT45 in Hodgkin's lymphoma. Heidebrecht, H.J., Claviez, A., Kruse, M.L., Pollmann, M., Buck, F., Harder, S., Tiemann, M., Dörffel, W., Parwaresch, R. Clin. Cancer Res. (2006) [Pubmed]
  3. Mitral regurgitation: quantification with 16-detector row CT--initial experience. Alkadhi, H., Wildermuth, S., Bettex, D.A., Plass, A., Baumert, B., Leschka, S., Desbiolles, L.M., Marincek, B., Boehm, T. Radiology. (2006) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities