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Gene Review

POLR2I  -  polymerase (RNA) II (DNA directed)...

Homo sapiens

Synonyms: DNA-directed RNA polymerase II subunit I, DNA-directed RNA polymerase II subunit RPB9, RNA polymerase II 14.5 kDa subunit, RNA polymerase II subunit B9, RPB14.5, ...
 
 
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High impact information on POLR2I

  • A human RNA polymerase II (pol II) complex was isolated from a HeLa-derived cell line that conditionally expresses an epitope-tagged RPB9 subunit of human pol II [1].
  • Cysteines characteristic of two zinc fingers are conserved in all three corresponding sequences and, like the yeast protein, the hRPB14.5 subunit exhibits zinc-binding activity [2].

References

  1. Properties of PC4 and an RNA polymerase II complex in directing activated and basal transcription in vitro. Wu, S.Y., Chiang, C.M. J. Biol. Chem. (1998) [Pubmed]
  2. Structure of the gene encoding the 14.5 kDa subunit of human RNA polymerase II. Acker, J., Wintzerith, M., Vigneron, M., Kedinger, C. Nucleic Acids Res. (1993) [Pubmed]
 
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