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Gene Review

PDS  -  phytoene desaturase

Hordeum vulgare

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Disease relevance of PDS

  • Moreover, an enhanced VIGS pds phenotype was observed using a different vector, based on barley stripe mosaic virus, in the monocotyledonous host barley [1].
  • A tobacco mosaic virus (TMV)-based vector carrying such inverted-repeats, homologous to a green fluorescent protein (gfp) transgene or an endogenous phytoene desaturase (pds) gene, generated a stronger and more pervasive VIGS phenotype than constructs carrying corresponding cDNA fragments in sense or antisense orientation [1].

High impact information on PDS

  • Barley infected with BSMV expressing barley, rice or maize PDS fragments became photo-bleached and accumulated phytoene (the substrate for PDS) in a manner similar to plants treated with the chemical inhibitor of PDS, norflurazon [2].
  • The VIGS visual phenotype varied from maintained during silencing of actin 1 transcript expression to transient with incomplete penetration through affected tissue during silencing of phytoene desaturase expression [3].

Associations of PDS with chemical compounds

  • In contrast, barley infected with wild-type BSMV, or BSMV expressing either N. benthamiana PDS or antisense green fluorescent protein (GFP), did not photo-bleach or accumulate phytoene [2].


  1. Enhancement of virus-induced gene silencing through viral-based production of inverted-repeats. Lacomme, C., Hrubikova, K., Hein, I. Plant J. (2003) [Pubmed]
  2. Barley stripe mosaic virus-induced gene silencing in a monocot plant. Holzberg, S., Brosio, P., Gross, C., Pogue, G.P. Plant J. (2002) [Pubmed]
  3. Characterization of a Brome mosaic virus strain and its use as a vector for gene silencing in monocotyledonous hosts. Ding, X.S., Schneider, W.L., Chaluvadi, S.R., Mian, M.A., Nelson, R.S. Mol. Plant Microbe Interact. (2006) [Pubmed]
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