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Gene Review

LSG1  -  large 60S subunit nuclear export GTPase 1

Homo sapiens

Synonyms: FLJ11301, Large subunit GTPase 1 homolog, hLsg1
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High impact information on LSG1

  • To understand the gene expression programs associated with senescence of somatic cells, we cloned two cDNAs, LSG1 and LSG2, that are preferentially expressed during this late developmental stage [1].
  • LSG1 also resembled genes encoding plant pathogenesis-related protein 1 (PR-1), while LSG2 showed similarities with genes encoding matrix metalloproteinases, including a gamete lytic enzyme of Chlamydomonas [1].


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