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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

URGCP  -  upregulator of cell proliferation

Homo sapiens

Synonyms: DKFZp666G166, DKFZp686O0457, FLJ20654, HBV X protein up-regulated gene 4 protein, HBxAg up-regulated gene 4 protein, ...
 
 
 
 
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Disease relevance of URG4

 

High impact information on URG4

  • The growth of GES-1 cells, which are immortalized human gastric epithelial mucosa cells with baseline URG4 expression, was accelerated by URG4 induction [1].
  • Downregulation of URG4 through URG4 small interfering RNA (siRNA) in SGC7901 and MKN28 cells, which had high endogenous URG4 expression, suppressed cell proliferation in both of these cells [1].
  • Upregulated gene 4 (URG4), a novel gene located on 7 chromosome (7p13), was found to contribute to hepatocarcinogenesis [1].
 

Analytical, diagnostic and therapeutic context of URG4

References

  1. Enhanced cell survival of gastric cancer cells by a novel gene URG4. Song, J., Xie, H., Lian, Z., Yang, G., Du, R., Du, Y., Zou, X., Jin, H., Gao, J., Liu, J., Fan, D. Neoplasia (2006) [Pubmed]
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