Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

BAI3 - brain-specific angiogenesis inhibitor 3

Homo sapiens

Synonyms: Brain-specific angiogenesis inhibitor 3, KIAA0550

Shiratsuchi, T. et al., Kee, H.J. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of BAI3

The decreased expressions of BAIs in high-grade gliomas were observed, but BAI3 expression was generally lower in malignant gliomas than in normal brain [1].
In the in vivo focal cerebral ischemia model, BAI3 expression decreased from 0.5 h after hypoxia until 8 h, but returned to control level after 24 h [1].
BAI3 expression was absent in two of nine glioblastoma cell lines examined and was significantly reduced in three of the remaining seven [2].

High impact information on BAI3

Like BAI1, these two genes, designated BAI2 and BAI3, were specifically expressed in brain, and are likely to be expressed in the same type of cells [2].
BAI1, BAI2 and BAI3 were mapped to 8q24, 1p35 and 6q12, respectively [2].

References

Expression of brain-specific angiogenesis inhibitor 3 (BAI3) in normal brain and implications for BAI3 in ischemia-induced brain angiogenesis and malignant glioma. Kee, H.J., Ahn, K.Y., Choi, K.C., Won Song, J., Heo, T., Jung, S., Kim, J.K., Bae, C.S., Kim, K.K. FEBS Lett. (2004) [Pubmed]
Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1). Shiratsuchi, T., Nishimori, H., Ichise, H., Nakamura, Y., Tokino, T. Cytogenet. Cell Genet. (1997) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

BAI3	Bos taurus
BAI3	Canis lupus familiaris
bai3	Danio rerio
BAI3	Gallus gallus
BAI3	Macaca mulatta
Bai3	Mus musculus
BAI3	Pan troglodytes
Bai3	Rattus norvegicus
bai3	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.