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Gene Review

ABCD4  -  ATP-binding cassette, sub-family D (ALD),...

Homo sapiens

Synonyms: ABC41, ATP-binding cassette sub-family D member 4, EST352188, MAHCJ, P70R, ...
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High impact information on ABCD4


Biological context of ABCD4

  • PMP69 might be a heterodimer partner for one of these proteins, thus playing a role in modifying the clinical course of ALD or, alternatively, in peroxisome biogenesis [5].

Other interactions of ABCD4


Analytical, diagnostic and therapeutic context of ABCD4


  1. Identification of a fourth half ABC transporter in the human peroxisomal membrane. Shani, N., Jimenez-Sanchez, G., Steel, G., Dean, M., Valle, D. Hum. Mol. Genet. (1997) [Pubmed]
  2. Novel mutations of FOXC1 and PITX2 in patients with Axenfeld-Rieger malformations. Weisschuh, N., Dressler, P., Schuettauf, F., Wolf, C., Wissinger, B., Gramer, E. Invest. Ophthalmol. Vis. Sci. (2006) [Pubmed]
  3. Genomic organization and chromosomal localization of the human peroxisomal membrane protein-1-like protein (PXMP1-L) gene encoding a peroxisomal ABC transporter. Holzinger, A., Roscher, A.A., Landgraf, P., Lichtner, P., Kammerer, S. FEBS Lett. (1998) [Pubmed]
  4. Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif. Landgraf, P., Mayerhofer, P.U., Polanetz, R., Roscher, A.A., Holzinger, A. Eur. J. Cell Biol. (2003) [Pubmed]
  5. Primary structure of human PMP69, a putative peroxisomal ABC-transporter. Holzinger, A., Kammerer, S., Roscher, A.A. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  6. Physical mapping of CHX10, ALDH6A1, and ABCD4 on bovine chromosome 10q34. Kuiper, H., Spötter, A., Williams, J.L., Distl, O., Drögemüller, C. Cytogenet. Genome Res. (2005) [Pubmed]
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