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Gene Review

BCAT2  -  branched chain amino-acid transaminase 2,...

Homo sapiens

Synonyms: BCAM, BCAT(m), BCATM, BCT2, Branched-chain-amino-acid aminotransferase, mitochondrial, ...
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High impact information on BCAT2

  • Aminotransferase activity of placental origin PP18 antigens was verified by structural analysis and by a coupled branched-chain aminotransferase/glutamate dehydrogenase assay [1].
  • Five different insert-length cDNAs encoding for soluble placental tissue protein 18 (PP18) variants were isolated by screening a human placental cDNA library using monospecific anti-PP18 serum [1].
  • Finally, the nomenclature BCAT1 for the cytosolic gene and BCAT2 for the mitochondrial BCAT gene is proposed [2].
  • Isolation and characterization of four new placental tissue proteins (PP18, PP19, PP20, PP21) [3].

Biological context of BCAT2


Analytical, diagnostic and therapeutic context of BCAT2

  • We detected the two PP18 variants in normal adult and fetal human tissues besides the mitochondrial (only PP18a) and cytosolic (only PP18b) fractions of term placenta with chemiluminescence Western blot analysis [1].


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