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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Matk  -  megakaryocyte-associated tyrosine kinase

Rattus norvegicus

Synonyms: Batk, Ctk, Megakaryocyte-associated tyrosine-protein kinase, Protein kinase BATK, Tyrosine-protein kinase CTK
 
 
 
 
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High impact information on Matk

  • Analysis of incompletely spliced Batk cDNAs suggests that the genomic structure of Batk is similar to that of Csk with identical exon/intron boundaries [1].
  • Batk resembles kinases of the Src family in that it contains a Src homology 2 (SH2) domain and an SH3 domain, followed by a tyrosine kinase domain [1].
  • In situ hybridization and Northern blot analysis show that Batk is widely distributed throughout the adult brain, being primarily expressed in neurons, including those of the hippocampus and cortex [1].

References

  1. Identification and characterization of Batk, a predominantly brain-specific non-receptor protein tyrosine kinase related to Csk. Kuo, S.S., Moran, P., Gripp, J., Armanini, M., Phillips, H.S., Goddard, A., Caras, I.W. J. Neurosci. Res. (1994) [Pubmed]
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