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Gene Review

NPVF  -  neuropeptide VF precursor

Homo sapiens

Synonyms: C7orf9, Pro-FMRFamide-related neuropeptide VF, RFRP
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High impact information on NPVF


Biological context of NPVF

  • RESULTS: The C7orf9 cDNA transcript consists of 1190 bp and is organized into 3 exons on the short arm of chromosome 7 within the critical region for CYMD [1].

Other interactions of NPVF

  • Results of our comprehensive mutation analysis suggests that C7orf9 is not the CYMD gene [1].

Analytical, diagnostic and therapeutic context of NPVF

  • C7orf9 was evaluated as a candidate gene for CYMD by DNA sequencing and Southern blot analysis in two affected individuals from an extended Dutch CYMD family [1].
  • We first cloned a cDNA encoding a putative GnIH receptor by a combination of 3' and 5' rapid amplification of cDNA ends (RACE) using PCR primers designed from the sequence for the receptor for rat RF-amide-related peptide (RFRP), an orthologous peptide of GnIH [2].


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