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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ube2g1  -  ubiquitin-conjugating enzyme E2G 1

Rattus norvegicus

Synonyms: E217K, UBC7, Ubc7, Ube2g, Ubiquitin carrier protein G1, ...
 
 
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High impact information on Ube2g1

  • Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+ [1].
  • The predicted amino acid sequence indicates that E217K is a 19 [2].
  • Analysis of testis RNA from rats of different ages showed that E217K mRNA was induced from days 15 to 30 [2].
  • Identification of rabbit reticulocyte E217K as a UBC7 homologue and functional characterization of its core domain loop [2].

References

  1. Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+. Webster, J.M., Tiwari, S., Weissman, A.M., Wojcikiewicz, R.J. J. Biol. Chem. (2003) [Pubmed]
  2. Identification of rabbit reticulocyte E217K as a UBC7 homologue and functional characterization of its core domain loop. Lin, H., Wing, S.S. J. Biol. Chem. (1999) [Pubmed]
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