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Gene Review

Ube2g1  -  ubiquitin-conjugating enzyme E2G 1

Rattus norvegicus

Synonyms: E217K, UBC7, Ubc7, Ube2g, Ubiquitin carrier protein G1, ...
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High impact information on Ube2g1

  • Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+ [1].
  • The predicted amino acid sequence indicates that E217K is a 19 [2].
  • Analysis of testis RNA from rats of different ages showed that E217K mRNA was induced from days 15 to 30 [2].
  • Identification of rabbit reticulocyte E217K as a UBC7 homologue and functional characterization of its core domain loop [2].


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