The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

MRPS11  -  mitochondrial ribosomal protein S11

Homo sapiens

Synonyms: 28S ribosomal protein S11, mitochondrial, Cervical cancer proto-oncogene 2 protein, FLJ22512, FLJ23406, HCC-2, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on MRPS11

  • We have cloned a gene for mitochondrial ribosomal protein S11 (RPS11), which is encoded in lower plants by the mitochondrial genome, in higher plants by the nuclear genome, demonstrating genetic information transfer from the mitochondrial genome to the nucleus during flowering plant evolution [1].
  • Functional analysis of the MRP S11 promoter showed that a Staf binding site in the promoter is required for both basal promoter activity and cisplatin-inducible activity [2].

Analytical, diagnostic and therapeutic context of MRPS11


  1. Targeting presequence acquisition after mitochondrial gene transfer to the nucleus occurs by duplication of existing targeting signals. Kadowaki, K., Kubo, N., Ozawa, K., Hirai, A. EMBO J. (1996) [Pubmed]
  2. ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA. Ishiguchi, H., Izumi, H., Torigoe, T., Yoshida, Y., Kubota, H., Tsuji, S., Kohno, K. Int. J. Cancer (2004) [Pubmed]
  3. Early hepatocellular carcinoma as an entity with a high rate of surgical cure. Takayama, T., Makuuchi, M., Hirohashi, S., Sakamoto, M., Yamamoto, J., Shimada, K., Kosuge, T., Okada, S., Takayasu, K., Yamasaki, S. Hepatology (1998) [Pubmed]
WikiGenes - Universities