Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Trak1 - trafficking protein, kinesin binding 1

Mus musculus

Synonyms: 2310001H13Rik, AI413908, AI467545, Trafficking kinesin-binding protein 1, hyrt, ...

Gilbert, S.L. et al., Hidaka, Y. et al.

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Disease relevance of Trak1

Recently three strains of herpes simplex virus type 1 (HSV-1), which did not react with Micro Trak Herpes (Syva Co.), were isolated by us from a patient with recurrent herpetic keratitis [1].

High impact information on Trak1

Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice [2].
We cloned the responsible gene, trafficking protein, kinesin binding 1 (Trak1), and showed that its protein product interacts with GABA(A) receptors [2].

References

Characterization of glycoprotein C-negative mutants of herpes simplex virus type 1 isolated from a patient with keratitis. Hidaka, Y., Sakuma, S., Kumano, Y., Minagawa, H., Mori, R. Arch. Virol. (1990) [Pubmed]
Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. Gilbert, S.L., Zhang, L., Forster, M.L., Anderson, J.R., Iwase, T., Soliven, B., Donahue, L.R., Sweet, H.O., Bronson, R.T., Davisson, M.T., Wollmann, R.L., Lahn, B.T. Nat. Genet. (2006) [Pubmed]

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AgaP_AGAP008801	Anopheles gambiae str. PEST
TRAK1	Canis lupus familiaris
milt	Drosophila melanogaster
TRAK1	Gallus gallus
TRAK1	Homo sapiens
TRAK1	Pan troglodytes
Trak1	Rattus norvegicus

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