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Gene Review

Trak1  -  trafficking protein, kinesin binding 1

Mus musculus

Synonyms: 2310001H13Rik, AI413908, AI467545, Trafficking kinesin-binding protein 1, hyrt, ...
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Disease relevance of Trak1


High impact information on Trak1

  • Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice [2].
  • We cloned the responsible gene, trafficking protein, kinesin binding 1 (Trak1), and showed that its protein product interacts with GABA(A) receptors [2].


  1. Characterization of glycoprotein C-negative mutants of herpes simplex virus type 1 isolated from a patient with keratitis. Hidaka, Y., Sakuma, S., Kumano, Y., Minagawa, H., Mori, R. Arch. Virol. (1990) [Pubmed]
  2. Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. Gilbert, S.L., Zhang, L., Forster, M.L., Anderson, J.R., Iwase, T., Soliven, B., Donahue, L.R., Sweet, H.O., Bronson, R.T., Davisson, M.T., Wollmann, R.L., Lahn, B.T. Nat. Genet. (2006) [Pubmed]
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