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Gene Review

TBX6  -  T-box 6

Homo sapiens

Synonyms: T-box protein 6, T-box transcription factor TBX6
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High impact information on TBX6


  1. WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Hofmann, M., Schuster-Gossler, K., Watabe-Rudolph, M., Aulehla, A., Herrmann, B.G., Gossler, A. Genes Dev. (2004) [Pubmed]
  2. The human TBX6 gene: cloning and assignment to chromosome 16p11.2. Papapetrou, C., Putt, W., Fox, M., Edwards, Y.H. Genomics (1999) [Pubmed]
  3. Both the functional specificity and autoregulative activity of two ascidian T-box genes HrBra and HrTbx6 are likely to be mediated by the DNA-binding domain. Takahashi, H., Mitani, Y., Satoh, N. Dev. Growth Differ. (2005) [Pubmed]
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