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Gene Review:

Bdh1 - 3-hydroxybutyrate dehydrogenase, type 1

Mus musculus

Synonyms: 2310032J20Rik, 3-hydroxybutyrate dehydrogenase, AI327223, BDH, Bdh, ...

Guder, W.G. et al., Lee, S. et al., Woltsche, M. et al., Rehm, S. et al.

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High impact information on Bdh1

By nitroblue tetrazolium enzyme histochemistry, 3-hydroxybutyrate dehydrogenase (seen predominantly in Clara cells) was localized in frozen tissue sections [1].
On the other hand, the mitochondrial marker enzymes, i.e. succinate dehydrogenase, cytochrome-c-oxidase and 3-hydroxybutyrate dehydrogenase, remained unchanged in altered hepatocytes [2].
As results, better (P<0.0001) development of 1-cell embryos was found in the Sigma than in the BDH; more blastocysts developed in Sigma oil washed with culture medium than in the others (37% vs. 0%) [3].
Renal ketone body metabolism. Distribution of 3-oxoacid CoA-transferase and 3-hydroxybutyrate dehydrogenase along the mouse nephron [4].
With the exception of the relatively low activity of 3-hydroxybutyrate dehydrogenase in the proximal convoluted tubule, the distribution pattern mirrors the distribution of mitochondria along the rat nephron [4].

Associations of Bdh1 with chemical compounds

Two enzymes of ketone body metabolism, 3-oxoacid CoA-transferase and 3-hydroxybutyrate dehydrogenase were measured with ultramicromethods to map their activities along single, dissected segments of mouse nephron [4].

References

Origin of spontaneous and transplacentally induced mouse lung tumors from alveolar type II cells. Rehm, S., Devor, D.E., Henneman, J.R., Ward, J.M. Exp. Lung Res. (1991) [Pubmed]
Enzyme-histochemical studies of griseofulvin-intoxicated mouse livers. Woltsche, M., Zatloukal, K., Denk, H. Liver (1991) [Pubmed]
Renovation of a drop embryo cultures system by using refined mineral oil and the effect of glucose and/or hemoglobin added to a serum-free medium. Lee, S., Cho, M., Kim, E., Kim, T., Lee, C., Han, J., Lim, J. J. Vet. Med. Sci. (2004) [Pubmed]
Renal ketone body metabolism. Distribution of 3-oxoacid CoA-transferase and 3-hydroxybutyrate dehydrogenase along the mouse nephron. Guder, W.G., Pürschel, S., Wirthensohn, G. Hoppe-Seyler's Z. Physiol. Chem. (1983) [Pubmed]

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