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Chemical Compound Review

Nitrotetrazolium Blue     2-[2-methoxy-4-[3-methoxy-4- [3-(4...

Synonyms: p-NITRO BT, nitro bt, BIMB1019, CHEMBL403063, CCRIS 9104, ...
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Disease relevance of Nitrotetrazolium Blue


Psychiatry related information on Nitrotetrazolium Blue


High impact information on Nitrotetrazolium Blue


Chemical compound and disease context of Nitrotetrazolium Blue


Biological context of Nitrotetrazolium Blue


Anatomical context of Nitrotetrazolium Blue


Associations of Nitrotetrazolium Blue with other chemical compounds

  • In vitro activation of resident and chemically-elicited cells by 72 h of exposure to mitogen- and antigen-prepared lymphokines, conditions that induce trypanocidal (5) and leishmanicidal activity (14), stimulated O2- and H2O2 release, and enhanced nitroblue tetrazolium reduction in response to toxoplasma ingestion [26].
  • During starvation, neurons reduced nitroblue tetrazolium to form the blue precipitate formazan, and the color change was blocked in neurons preloaded with superoxide dismutase [27].
  • Nitroprusside and NaNO2, which activate cytosolic guanylate cyclase and increase the intracellular cGMP concentration, induced granulocytic differentiation of the human promyelocytic cell line HL-60; differentiation was measured by acquisition of the OKM1 antigen, morphological changes, and nitroblue tetrazolium reduction [28].
  • Other tests showed the patient's granulocytes to engulf latex particles normally, but to have impaired reduction of nitroblue tetrazolium and ferricytochrome-c as well as reduced iodination [29].
  • No abnormalities of the PHA cells, as compared to normal control cells, were found when tested for quantitative leukocyte enzyme activities, nitroblue tetrazolium reduction, hexose monophosphate shunt activity, superoxide production, generation of chemiluminescence, or iodination [30].

Gene context of Nitrotetrazolium Blue


Analytical, diagnostic and therapeutic context of Nitrotetrazolium Blue


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