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Gene Review

WNT7B  -  wingless-type MMTV integration site family...

Homo sapiens

Synonyms: Protein Wnt-7b
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Disease relevance of WNT7B


High impact information on WNT7B

  • Here, expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer were investigated [2].
  • Only partial coding sequence of human WNT7B is reported so far, and human genome draft sequence corresponding to the WNT7B gene in human chromosome 22q13 region is not available at present [1].
  • WNT7B encoded a 349-amino-acid polypeptide with three N-linked glycosylation sites and consensus amino-acid residues conserved among members of the WNT family [1].

Associations of WNT7B with chemical compounds


Analytical, diagnostic and therapeutic context of WNT7B


  1. Molecular cloning and characterization of human WNT7B. Kirikoshi, H., Sekihara, H., Katoh, M. Int. J. Oncol. (2001) [Pubmed]
  2. Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer. Kirikoshi, H., Katoh, M. Int. J. Oncol. (2002) [Pubmed]
  3. Assignment of WNT7B to human chromosome band 22q13 by in situ hybridization. van Bokhoven, H., Kissing, J., Schepens, M., van Beersum, S., Simons, A., Riegman, P., McMahon, J.A., McMahon, A.P., Brunner, H.G. Cytogenet. Cell Genet. (1997) [Pubmed]
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