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Gene Review:

Etnk1 - ethanolamine kinase 1

Mus musculus

Synonyms: 1110061E11Rik, 4930555L11Rik, AI195356, AI841245, C80956, ...

Dixon, R.M., Tian, Y. et al., Upreti, R.K. et al., Aoyama, C. et al., Aoyama, C. et al.

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High impact information on Etnk1

Ethanolamine kinase catalyzes the first step in the CDP-ethanolamine pathway for the formation of the major membrane phospholipid phosphatidylethanolamine (PtdEtn) [1].
Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta [2].
In the lymphomatous liver, both ethanolamine kinase and PE:CTP cytidylyltransferase had lower activities than in the normal liver, and there was evidence for a higher activity of ethanolamine base-exchange enzyme [3].

Associations of Etnk1 with chemical compounds

The effect of intake of ethanol on choline- and ethanolamine kinase activities in liver and brain tissues of mice was studied over a period of 31 days [4].

Analytical, diagnostic and therapeutic context of Etnk1

Molecular cloning of mouse choline kinase and choline/ethanolamine kinase: their sequence comparison to the respective rat homologs [5].

References

Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. Tian, Y., Jackson, P., Gunter, C., Wang, J., Rock, C.O., Jackowski, S. J. Biol. Chem. (2006) [Pubmed]
Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta. Aoyama, C., Yamazaki, N., Terada, H., Ishidate, K. J. Lipid Res. (2000) [Pubmed]
Phosphatidylethanolamine synthesis in the normal and lymphomatous mouse liver; a 13C NMR study. Dixon, R.M. Anticancer Res. (1996) [Pubmed]
Effect of oral ethanol administration on choline and ethanolamine phosphorylating activities in liver and brain of mice. Upreti, R.K., Shanker, R. Toxicology (1978) [Pubmed]
Molecular cloning of mouse choline kinase and choline/ethanolamine kinase: their sequence comparison to the respective rat homologs. Aoyama, C., Nakashima, K., Ishidate, K. Biochim. Biophys. Acta (1998) [Pubmed]

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