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Chemical Compound Review

colamine     2-aminoethanol

Synonyms: Glycinol, Kolamin, Olamine, Olaminl, Etanolamina, ...
 
 
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Disease relevance of colamine

 

Psychiatry related information on colamine

 

High impact information on colamine

 

Chemical compound and disease context of colamine

 

Biological context of colamine

  • Lysis of pneumococci by the surfactant fraction appeared to be mediated by a detergent-like activation of pneumococcal autolysin, in that bacteriolysis was prevented by substitution of ethanolamine for choline in pneumococcal cell walls, and a pneumococcal transformant that lacked autolysin was not lysed [19].
  • A specific function of inositol acylation in trypanosomes may be to enhance the efficiency of ethanolamine phosphate addition to the Man3GlcN-(acyl)PI intermediate [20].
  • Addition of PE or ethanolamine, a precursor of PE synthesis, restored the cell surface PE on the cleavage furrow and normal cytokinesis [21].
  • Evaluation of the cells' energetics indicated that the enhanced production of phosphoethanolamine is probably not due to ethanolamine phosphorylation [22].
  • In addition, both BGTC and BGSC present also a high transfection activity when formulated as liposomes with the neutral phospholipid dioleoylphosphatidyl ethanolamine [23].
 

Anatomical context of colamine

  • The surfactant fraction readily killed pneumococci containing ethanolamine or the autolysin-defective transformant, and studies with tritiated methyl-D-glucose loading and release showed that killing was associated with increased bacterial cell membrane permeability [19].
  • Compared with the normal erythrocyte, the outer membrane leaflet of the deoxygenated, reversibly sickled cells (RSC) and irreversibly sickled cells (ISC) was enriched in phosphatidyl ethanolamine in addition to containing phosphatidyl serine [24].
  • Duodenal ulcerogens, unlike the nonulcerogen but toxic analogue ethanolamine, caused an early disruption of the myoelectric migrating complex, a marked increase in the spiking activity, and a decrease in the frequency of the slow waves in the duodenum [25].
  • The glycosomes were surrounded by a single membrane and contained as phospholipids only phosphatidyl choline and phosphatidyl ethanolamine in a ratio of 2:1 [26].
  • Ethanolamine modulates the rate of rat hepatocyte proliferation in vitro and in vivo [3].
 

Associations of colamine with other chemical compounds

 

Gene context of colamine

 

Analytical, diagnostic and therapeutic context of colamine

References

  1. Letter: Dimethyl aminoethanol in blepharospasm and hemifacial spasm. Dahdaleh, M.P., Small, M., Thomas, D.J. N. Engl. J. Med. (1975) [Pubmed]
  2. Evidence for the B12-dependent enzyme ethanolamine deaminase in Salmonella. Chang, G.W., Chang, J.T. Nature (1975) [Pubmed]
  3. Ethanolamine modulates the rate of rat hepatocyte proliferation in vitro and in vivo. Sasaki, H., Kume, H., Nemoto, A., Narisawa, S., Takahashi, N. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  4. Lysoplasmenylethanolamine accumulation in ischemic/reperfused isolated fatty acid-perfused hearts. Davies, N.J., Schulz, R., Olley, P.M., Strynadka, K.D., Panas, D.L., Lopaschuk, G.D. Circ. Res. (1992) [Pubmed]
  5. Differential accumulation of diacyl and plasmalogenic diglycerides during myocardial ischemia. Ford, D.A., Gross, R.W. Circ. Res. (1989) [Pubmed]
  6. Membrane instability, plasmalogen content, and Alzheimer's disease. Ginsberg, L., Xuereb, J.H., Gershfeld, N.L. J. Neurochem. (1998) [Pubmed]
  7. Phosphoethanolamine and ethanolamine are decreased in Alzheimer's disease and Huntington's disease. Ellison, D.W., Beal, M.F., Martin, J.B. Brain Res. (1987) [Pubmed]
  8. Amines compounds as inhibitors of PCDD/Fs de novo formation on sintering process fly ash. Xhrouet, C., Nadin, C., De Pauw, E. Environ. Sci. Technol. (2002) [Pubmed]
  9. Studies on the embryopathic effects of ethanolamine in Long-Evans rats: preferential embryopathy in pups contiguous with male siblings in utero. Mankes, R.F. Teratog., Carcinog. Mutagen. (1986) [Pubmed]
  10. Scrapie prion protein contains a phosphatidylinositol glycolipid. Stahl, N., Borchelt, D.R., Hsiao, K., Prusiner, S.B. Cell (1987) [Pubmed]
  11. Magnetic field effects on B12 ethanolamine ammonia lyase: evidence for a radical mechanism. Harkins, T.T., Grissom, C.B. Science (1994) [Pubmed]
  12. Isolation of a human myocardial cytosolic phospholipase A2 isoform. Fast atom bombardment mass spectroscopic and reverse-phase high pressure liquid chromatography identification of choline and ethanolamine glycerophospholipid substrates. Hazen, S.L., Hall, C.R., Ford, D.A., Gross, R.W. J. Clin. Invest. (1993) [Pubmed]
  13. Bradykinin-activated membrane-associated phospholipase C in Madin-Darby canine kidney cells. Portilla, D., Morrissey, J., Morrison, A.R. J. Clin. Invest. (1988) [Pubmed]
  14. Cobalamin (coenzyme B12): synthesis and biological significance. Roth, J.R., Lawrence, J.G., Bobik, T.A. Annu. Rev. Microbiol. (1996) [Pubmed]
  15. Human vitamin B12 absorption measurement by accelerator mass spectrometry using specifically labeled (14)C-cobalamin. Carkeet, C., Dueker, S.R., Lango, J., Buchholz, B.A., Miller, J.W., Green, R., Hammock, B.D., Roth, J.R., Anderson, P.J. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  16. The utilization of ethanolamine and serine for ethanolamine phosphoglyceride synthesis by human Y79 retinoblastoma cells. Yorek, M.A., Rosario, R.T., Dudley, D.T., Spector, A.A. J. Biol. Chem. (1985) [Pubmed]
  17. Phospholipid metabolism in cancer cells monitored by 31P NMR spectroscopy. Daly, P.F., Lyon, R.C., Faustino, P.J., Cohen, J.S. J. Biol. Chem. (1987) [Pubmed]
  18. Global regulation by CsrA in Salmonella typhimurium. Lawhon, S.D., Frye, J.G., Suyemoto, M., Porwollik, S., McClelland, M., Altier, C. Mol. Microbiol. (2003) [Pubmed]
  19. Detection and partial characterization of antibacterial factor(s) in alveolar lining material of rats. Coonrod, J.D., Yoneda, K. J. Clin. Invest. (1983) [Pubmed]
  20. The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei. Güther, M.L., Ferguson, M.A. EMBO J. (1995) [Pubmed]
  21. An essential role for a membrane lipid in cytokinesis. Regulation of contractile ring disassembly by redistribution of phosphatidylethanolamine. Emoto, K., Umeda, M. J. Cell Biol. (2000) [Pubmed]
  22. Stimulation of cAMP and phosphomonoester production by melanotropin in melanoma cells: 31P NMR studies. Degani, H., DeJordy, J.O., Salomon, Y. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  23. Guanidinium-cholesterol cationic lipids: efficient vectors for the transfection of eukaryotic cells. Vigneron, J.P., Oudrhiri, N., Fauquet, M., Vergely, L., Bradley, J.C., Basseville, M., Lehn, P., Lehn, J.M. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  24. Abnormalities in membrane phospholipid organization in sickled erythrocytes. Lubin, B., Chiu, D., Bastacky, J., Roelofsen, B., Van Deenen, L.L. J. Clin. Invest. (1981) [Pubmed]
  25. Duodenal ulcerogens cysteamine and propionitrile induce gastroduodenal motility alterations in the rat. Pihan, G., Kline, T.J., Hollenberg, N.K., Szabo, S. Gastroenterology (1985) [Pubmed]
  26. Purification, morphometric analysis, and characterization of the glycosomes (microbodies) of the protozoan hemoflagellate Trypanosoma brucei. Opperdoes, F.R., Baudhuin, P., Coppens, I., De Roe, C., Edwards, S.W., Weijers, P.J., Misset, O. J. Cell Biol. (1984) [Pubmed]
  27. Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan. Brunner, G., Gabrilove, J., Rifkin, D.B., Wilson, E.L. J. Cell Biol. (1991) [Pubmed]
  28. Carcinoembryonic antigen is anchored to membranes by covalent attachment to a glycosylphosphatidylinositol moiety: identification of the ethanolamine linkage site. Hefta, S.A., Hefta, L.J., Lee, T.D., Paxton, R.J., Shively, J.E. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  29. Epolones induce erythropoietin expression via hypoxia-inducible factor-1 alpha activation. Wanner, R.M., Spielmann, P., Stroka, D.M., Camenisch, G., Camenisch, I., Scheid, A., Houck, D.R., Bauer, C., Gassmann, M., Wenger, R.H. Blood (2000) [Pubmed]
  30. Ethanolamine metabolism in cultured bovine aortic endothelial cells. Lipton, B.A., Davidson, E.P., Ginsberg, B.H., Yorek, M.A. J. Biol. Chem. (1990) [Pubmed]
  31. Specific pools of phospholipids are used for lipoprotein secretion by cultured rat hepatocytes. Vance, J.E., Vance, D.E. J. Biol. Chem. (1986) [Pubmed]
  32. sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae. Nucleotide sequence of the EPT1 gene and comparison of the CPT1 and EPT1 gene products. Hjelmstad, R.H., Bell, R.M. J. Biol. Chem. (1991) [Pubmed]
  33. Phosphatidylserine decarboxylase 2 of Saccharomyces cerevisiáe. Cloning and mapping of the gene, heterologous expression, and creation of the null allele. Trotter, P.J., Pedretti, J., Yates, R., Voelker, D.R. J. Biol. Chem. (1995) [Pubmed]
  34. Glycosylphosphatidylinositol (GPI) proteins of Saccharomyces cerevisiae contain ethanolamine phosphate groups on the alpha1,4-linked mannose of the GPI anchor. Imhof, I., Flury, I., Vionnet, C., Roubaty, C., Egger, D., Conzelmann, A. J. Biol. Chem. (2004) [Pubmed]
  35. Phosphatidylethanolamine is the donor of the ethanolamine residue linking a glycosylphosphatidylinositol anchor to protein. Menon, A.K., Stevens, V.L. J. Biol. Chem. (1992) [Pubmed]
  36. Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. Tian, Y., Jackson, P., Gunter, C., Wang, J., Rock, C.O., Jackowski, S. J. Biol. Chem. (2006) [Pubmed]
  37. Effects of ethanolamine and choline on thiotepa cellular accumulation and cytotoxicity in L1210 cells. Egorin, M.J., Snyder, S.W., Wietharn, B.E. Cancer Res. (1990) [Pubmed]
  38. Regulation of the cytidine phospholipid pathways in human cancer cells and effects of 1-beta-D-arabinofuranosylcytosine: a noninvasive 31P nuclear magnetic resonance study. Daly, P.F., Zugmaier, G., Sandler, D., Carpen, M., Myers, C.E., Cohen, J.S. Cancer Res. (1990) [Pubmed]
  39. Rapid purification of phospholipase A2 from Crotalus adamanteus venom by affinity chromatography. Rock, C.O., Snyder, F. J. Biol. Chem. (1975) [Pubmed]
  40. [3H]myoinositol incorporation into phospholipids in liver microsomes from humans with and without type II diabetes. The lack of synthesis of glycosylphosphatidylinositol, precursor of the insulin mediator inositol phosphate glycan. Thakkar, J.K., Raju, M.S., Kennington, A.S., Foil, B., Caro, J.F. J. Biol. Chem. (1990) [Pubmed]
 
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