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Gene Review:

CRSA - Craniosynostosis, Adelaide type

Homo sapiens

Scopel, V. et al., Pae, A.N. et al.

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Disease relevance of CRSA

Two series of oxazolidinone derivatives having substituted isoxazoles were synthesized and tested for antibacterial activities against several Gram-positive strains including the resistant strains of Staphylococcus and Enterococcus, such as MRSA, CRSA, MSSA and VRE [1].
The purpose of this study was to evaluate the effectiveness of the therapy with a centric relation stabilization appliance (CRSA) in patients with temporomandibular disorders of myogenous origin by electromyography and compare the results with two asymptomatic control groups [2].

High impact information on CRSA

Treatment with the CRSA reduced the activity index, although the prevalence of the temporal muscle over the masseter was maintained [2].

References

Synthesis and in vitro activity of new oxazolidinone antibacterial agents having substituted isoxazoles. Pae, A.N., Kim, H.Y., Joo, H.J., Kim, B.H., Cho, Y.S., Choi, K.I., Choi, J.H., Koh, H.Y. Bioorg. Med. Chem. Lett. (1999) [Pubmed]
An electromyographic study of masseter and anterior temporalis muscles in extra-articular myogenous TMJ pain patients compared to an asymptomatic and normal population. Scopel, V., Alves da Costa, G.S., Urias, D. Cranio : the journal of craniomandibular practice. (2005) [Pubmed]

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