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Gene Review

ATHL1  -  ATH1, acid trehalase-like 1 (yeast)

Homo sapiens

Synonyms: Acid trehalase-like protein 1, FLJ22635
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Disease relevance of ATHL1

  • This study used a cross-sectional comparison of endurance athletes (n=20; ATHL) exhibiting resting bradycardia and age-matched nonathletes (n=12; CRTL) to indirectly assess training effects on amplitude and timing characteristics of respiratory sinus arrhythmia (RSA) [1].

High impact information on ATHL1

  • Under baseline SP conditions, heart rate was lower in ATHL (62.6+/-6.5 vs. 75.2+/-9 beats/min; p<0.05) while blood pressure (BP), breath cycle duration, tidal volume, and ventilatory drive were similar in both groups [1].


  1. Enhanced cardiac vagal efferent activity does not explain training-induced bradycardia. Scott, A.S., Eberhard, A., Ofir, D., Benchetrit, G., Dinh, T.P., Calabrese, P., Lesiuk, V., Perrault, H. Autonomic neuroscience : basic & clinical. (2004) [Pubmed]
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