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Gene Review:

LKP2 - LOV KELCH protein 2

Arabidopsis thaliana

Synonyms: ADAGIO 2, ADO2

Schultz, T.F. et al., Fukamatsu, Y. et al., Yasuhara, M. et al.

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High impact information on LKP2

A third member of the ZTL gene family was identified in the Arabidopsis genome and was named LKP2 (for LOV kelch protein2) [1].
The overexpression of LKP2 resulted in arrhythmic phenotypes for a number of circadian clock outputs in both constant light and constant darkness, long hypocotyls under multiple fluences of both red and blue light, and a loss of photoperiodic control of flowering time [1].
The LKP2-binding site in CO or COL1 was near the center of each protein [2].
When LKP2 was fused with cyan fluorescent proein (CFP) and transiently expressed in onion epidermal cells, CFP-LKP2 signals were localized in the nucleus and cytosol [2].
The LOV domain of LKP2 was shown to be necessary and sufficient for the interaction with TOC1 [3].

Other interactions of LKP2

However, co-expression of CFP-LKP2 with YFP fused to either CO or COL1 resulted in the recruitment of CFP-LKP2 in nuclear bodies [2].

References

A role for LKP2 in the circadian clock of Arabidopsis. Schultz, T.F., Kiyosue, T., Yanovsky, M., Wada, M., Kay, S.A. Plant Cell (2001) [Pubmed]
Identification of LOV KELCH PROTEIN2 (LKP2)-interacting factors that can recruit LKP2 to nuclear bodies. Fukamatsu, Y., Mitsui, S., Yasuhara, M., Tokioka, Y., Ihara, N., Fujita, S., Kiyosue, T. Plant Cell Physiol. (2005) [Pubmed]
Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis. Yasuhara, M., Mitsui, S., Hirano, H., Takanabe, R., Tokioka, Y., Ihara, N., Komatsu, A., Seki, M., Shinozaki, K., Kiyosue, T. J. Exp. Bot. (2004) [Pubmed]

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