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Gene Review:

VMP1 - vacuole membrane protein 1

Homo sapiens

Synonyms: EPG3, HSPC292, TANGO5, TDC1, TMEM49, ...

Dusetti, N.J. et al.

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Disease relevance of TMEM49

Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation [1].

High impact information on TMEM49

Expression of this protein promoted the formation of intracytoplasmatic vacuoles and VMP1/EGFP was located to the membranes of these vacuoles [1].
VMP1/EGFP fusion protein was located to the Golgi apparatus and the endoplasmic reticulum area [1].

Anatomical context of TMEM49

In this report, we describe the cloning, sequencing, and expression pattern of a new gene, named VMP1 (vacuole membrane protein 1) [1].

Analytical, diagnostic and therapeutic context of TMEM49

In situ hybridization studies revealed that pancreatic expression of VMP1 mRNAs was restricted to the acinar cells [1].

References

Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation. Dusetti, N.J., Jiang, Y., Vaccaro, M.I., Tomasini, R., Azizi Samir, A., Calvo, E.L., Ropolo, A., Fiedler, F., Mallo, G.V., Dagorn, J.C., Iovanna, J.L. Biochem. Biophys. Res. Commun. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP010304	Anopheles gambiae str. PEST
AT4G14950	Arabidopsis thaliana
AT1G05360	Arabidopsis thaliana
VMP1	Bos taurus
epg-3	Caenorhabditis elegans
VMP1	Canis lupus familiaris
vmp1	Danio rerio
Tango5	Drosophila melanogaster
VMP1	Gallus gallus
Vmp1	Mus musculus
Os01g0778700	Oryza sativa Japonica Group
VMP1	Pan troglodytes
Vmp1	Rattus norvegicus
vmp1	Xenopus (Silurana) tropicalis

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