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Gene Review:

CYCD2;1 - cyclin-D2-1

Arabidopsis thaliana

Synonyms: ATCYCD2;1, Cyclin D2;1, F14M13.11, F14M13_11

Boucheron, E. et al., Menges, M. et al., Soni, R. et al., Fuerst, R.A. et al.

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Disease relevance of CYCD2;1

Transgenic tobacco lines expressing Arath-CYCD2 or Arath-CYCD3 genes under a cauliflower mosaic virus 35S promoter are modified in the timing of their development, but not in the phenotype of their vegetative organs [1].

High impact information on CYCD2;1

Synchronized cultures confirm that CYCD3;1-expressing (but not CYCD2;1-expressing) cells show increased G2-phase length and delayed activation of mitotic genes such as B-type cyclins, suggesting that CYCD3;1 has a specific G1/S role [2].
CYCD2 (delta 2) transcript levels were largely unaffected by the readdition of phytohormones or nitrate to the growth medium, and remained constant throughout the cell cycle in suspension-culture cells [3].
These changes reveal a particular sensitivity of the corpus cells (L3) to Arath-CYCD2 over-expression and suggest a role for CYCD2 in controlling the planes of cell division in these cells [1].

Associations of CYCD2;1 with chemical compounds

In support of this hypothesis, we show that, on restimulation of suspension-cultured cells, cyclin delta 3 is rapidly induced by the plant growth regulator cytokinin and cyclin delta 2 is induced by carbon source [4].

References

Ectopic expression of Arabidopsis CYCD2 and CYCD3 in tobacco has distinct effects on the structural organization of the shoot apical meristem. Boucheron, E., Healy, J.H., Bajon, C., Sauvanet, A., Rembur, J., Noin, M., Sekine, M., Riou Khamlichi, C., Murray, J.A., Van Onckelen, H., Chriqui, D. J. Exp. Bot. (2005) [Pubmed]
The D-type cyclin CYCD3;1 is limiting for the G1-to-S-phase transition in Arabidopsis. Menges, M., Samland, A.K., Planchais, S., Murray, J.A. Plant Cell (2006) [Pubmed]
Modulation of cyclin transcript levels in cultured cells of Arabidopsis thaliana. Fuerst, R.A., Soni, R., Murray, J.A., Lindsey, K. Plant Physiol. (1996) [Pubmed]
A family of cyclin D homologs from plants differentially controlled by growth regulators and containing the conserved retinoblastoma protein interaction motif. Soni, R., Carmichael, J.P., Shah, Z.H., Murray, J.A. Plant Cell (1995) [Pubmed]

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CYCD4;1	Arabidopsis thaliana
CYCD4;2	Arabidopsis thaliana
Os07g0620800	Oryza sativa Japonica Group
Os08g0479300	Oryza sativa Japonica Group
Os09g0466100	Oryza sativa Japonica Group

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