Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

ABCB19 - ABC transporter B family member 19

Arabidopsis thaliana

Synonyms: ATABCB19, ATMDR1, ATMDR11, ATP BINDING CASSETTE SUBFAMILY B19, ATP binding cassette subfamily B19, ...

Bouchard, R. et al., Lin, R. et al., Noh, B. et al.

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High impact information on ATMDR11/ATPGP19/MDR1/MDR11/PGP19

Arabidopsis possesses several genes related to the multidrug resistance (MDR) genes of animals, one of which, AtMDR1, was shown to be induced by the hormone auxin [1].
Employing an IAA-specific microelectrode demonstrated that IAA influx in the root elongation zone was perturbed and apically shifted in pgp1/pgp19 and twd1 roots [2].
Constitutive overexpression of PGP1 and PGP19, but not TWD1, enhanced auxin export [2].
Together, our results suggest that AtMDR1 and AtPGP1 regulate Arabidopsis (Arabidopsis thaliana) photomorphogenesis and multiple aspects of root development by mediating polar auxin transport [3].

References

Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxin-mediated development. Noh, B., Murphy, A.S., Spalding, E.P. Plant Cell (2001) [Pubmed]
Immunophilin-like TWISTED DWARF1 Modulates Auxin Efflux Activities of Arabidopsis P-glycoproteins. Bouchard, R., Bailly, A., Blakeslee, J.J., Oehring, S.C., Vincenzetti, V., Lee, O.R., Paponov, I., Palme, K., Mancuso, S., Murphy, A.S., Schulz, B., Geisler, M. J. Biol. Chem. (2006) [Pubmed]
Two homologous ATP-binding cassette transporter proteins, AtMDR1 and AtPGP1, regulate Arabidopsis photomorphogenesis and root development by mediating polar auxin transport. Lin, R., Wang, H. Plant Physiol. (2005) [Pubmed]

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abcb5	Danio rerio
LOC420606	Gallus gallus
MGG_02348	Magnaporthe oryzae 70-15
Os04g0459000	Oryza sativa Japonica Group
LOC100494753	Xenopus (Silurana) tropicalis

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