Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

SIGC - RNA polymerase sigma-subunit C

Arabidopsis thaliana

Synonyms: RNA POLYMERASE SIGMA-SUBUNIT, RNApolymerase sigma-subunit C, SIG3, SIGMA FACTOR 3

Isono, K. et al., Privat, I. et al., Lahiri, S.D. et al., Zghidi, W. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on SIGC

We have cloned three distinct cDNAs, designated SIG1, SIG2, and SIG3, for polypeptides possessing amino acid sequences for domains conserved in sigma70 factors of bacterial RNA polymerases from the higher plant Arabidopsis thaliana [1].
SIG2 is present as a soluble factor while SIG3 is partly attached to the plastid membranes [2].
Therefore, SIG3 cannot substitute for SIG2 function in early chloroplast biogenesis, when plastid membranes are not yet made up [2].
The SIG3-specific promoter region has been localized on the DNA by primer extension and mRNA capping experiments [3].
Two of the maize cDNAs, sig1 and sig3, encode NH2-terminal transit peptides which direct the uptake of a heterologous protein into chloroplasts in vitro [4].

Biological context of SIGC

Transient expression assays using green fluorescent protein demonstrated that N-terminal regions of the SIG2 and SIG3 ORFs could function as transit peptides for import into chloroplasts [1].

References

Leaf-specifically expressed genes for polypeptides destined for chloroplasts with domains of sigma70 factors of bacterial RNA polymerases in Arabidopsis thaliana. Isono, K., Shimizu, M., Yoshimoto, K., Niwa, Y., Satoh, K., Yokota, A., Kobayashi, H. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
Characterization of Arabidopsis plastid sigma-like transcription factors SIG1, SIG2 and SIG3. Privat, I., Hakimi, M.A., Buhot, L., Favory, J.J., Mache-Lerbs, S. Plant Mol. Biol. (2003) [Pubmed]
Nucleus-encoded plastid sigma factor SIG3 transcribes specifically the psbN gene in plastids. Zghidi, W., Merendino, L., Cottet, A., Mache, R., Lerbs-Mache, S. Nucleic Acids Res. (2007) [Pubmed]
Tissue-specific and light-dependent expression within a family of nuclear-encoded sigma-like factors from Zea mays. Lahiri, S.D., Yao, J., McCumbers, C., Allison, L.A. Mol. Cell Biol. Res. Commun. (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.