High impact information on CLB6

• The signal transduction pathways that lead to chloroplast biogenesis in plants are largely unknown [1].
• Cytokinins are essential plant hormones that are involved in shoot meristem and leaf formation, cell division, chloroplast biogenesis and senescence [2].
• The major protein import receptor of plastids is essential for chloroplast biogenesis [3].
• During this chloroplast biogenesis, the photosynthetic apparatus is rapidly assembled, mostly from nuclear-encoded imported proteins, which are synthesized in the cytosol as precursors with cleavable amino-terminal targeting sequences called transit sequences [3].
• These data support the function of Toc159 as a selective import receptor for the targeting of a set of preproteins required for chloroplast biogenesis [4].

Biological context of CLB6

• A double mutant of cia5 At tic20-I had the same phenotype as the At tic20-I single mutant, suggesting that CIA5 and At Tic20 function similarly in chloroplast biogenesis, with At Tic20 functioning earlier in development [5].
• This difference also suggests that the function of cpSRP43 is most likely restricted to protein targeting into the thylakoid membrane, whereas cpSRP54 may be involved in an additional process(es), such as chloroplast biogenesis, perhaps through chloroplast-ribosomal association with chloroplast ribosomes [6].
• We conclude that ClpR2 cannot be functionally replaced by other ClpP/R homologues and that the ClpPRS complex is central to chloroplast biogenesis, thylakoid protein homeostasis, and plant development [7].
• Downregulation of ClpR2 leads to reduced accumulation of the ClpPRS protease complex and defects in chloroplast biogenesis in Arabidopsis [7].
• Recent experiments with Chlamydomonas have substantially advanced our understanding of several aspects of photosynthesis, including chloroplast biogenesis, structure-function relationships in photosynthetic complexes, and environmental regulation [8].

Anatomical context of CLB6

• FtsH protease is important in chloroplast biogenesis and thylakoid maintenance [9].

Associations of CLB6 with chemical compounds

• We conclude that de novo purine biosynthesis is not only important for cell division, but also for chloroplast biogenesis [10].
• Chloroplast biogenesis 92: In situ screening for divinyl chlorophyll(ide) a reductase mutants by spectrofluorometry [11].
• Important differences of atrazine tolerance between sucrose and glucose treatments showed that activation of chloroplast biogenesis per se could not account for induced tolerance [12].

Other interactions of CLB6

• The IMMUTANS variegation locus of Arabidopsis defines a mitochondrial alternative oxidase homolog that functions during early chloroplast biogenesis [13].
• The present results demonstrated that Chl biosynthesis and chloroplast biogenesis in A. thaliana are controlled by three POR isoforms, which are differentially controlled by light and development [14].
• In addition to influencing embryo development EMB506 also affects chloroplast biogenesis [15].
• The yellow variegated mutant of Arabidopsis is plastid autonomous and delayed in chloroplast biogenesis [16].

Analytical, diagnostic and therapeutic context of CLB6

• This locus was named FARFADET and resulted in pleiotropic effects on chloroplast biogenesis, cell size and differentiation, organ size and number [17].

References