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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review

RCE1  -  RUB1 conjugating enzyme 1

Arabidopsis thaliana

Synonyms: AP22.40, AP22_40
 
 
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High impact information on RCE1

  • In addition, we show that RCE1 interacts directly with the RING protein RBX1 and is present in a stable complex with SCF [1].
  • A mutation in the RCE1 gene results in a phenotype like that of the axr1 mutant [1].
  • Positional cloning of the mutation resulted in identification of a 49-bp deletion in RCE1 (related to ubiquitin 1 (RUB1)-conjugating enzyme), which has been demonstrated to be responsible for covalent attachment of RUB1 to the SCF (Skpl Cdc 53 F-box) ubiquitin ligase complex to modify its activity [2].
 

Associations of RCE1 with chemical compounds

  • Most strikingly, plants deficient in both RCE1 and AXR1 have an embryonic phenotype similar to mp and bdl mutants, previously shown to be deficient in auxin signaling [1].

References

 
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