Disease relevance of ATMYB33/MYB33

• However, myb33 myb65 sterility was conditional, where fertility increased both under higher light or lower temperature conditions [1].
• In myb33 myb65 anthers, the tapetum undergoes hypertrophy at the pollen mother cell stage, resulting in premeiotic abortion of pollen development [1].

High impact information on ATMYB33/MYB33

• Neither single mutant displayed a phenotype, implying that MYB33 and MYB65 are functionally redundant [1].
• A microRNA target sequence is present in the MYB genes, and mutating this sequence in the MYB33:GUS fusion results in an expanded expression pattern, in tissues similar to that observed in the promoter-GUS lines, implying that the microRNA target sequence is restricting MYB33 expression [1].
• Causality was suggested by the finding that, with GA treatment, plants flowered in short days, AtMYB33 expression increased at the shoot apex, and the petioles elongated and grew erect [2].

References