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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TGA4  -  transcription factor TGA4

Arabidopsis thaliana

Synonyms: OBF4, OCS BINDING ELEMENT 4, OCS ELEMENT BINDING FACTOR 4, OCTOPINE SYNTHASE ELEMENT-BINDING PROTEIN, T31P16.20, ...
 
 
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High impact information on TGA4

  • Genes for ocs element binding factors (OBFs), which belong to a specific class of highly conserved, plant basic domain-leucine zipper transcription factors, have been isolated and include the Arabidopsis OBF4 and OBF5 genes [1].
  • To characterize proteins that modulate the activity of the OBF proteins, we screened an Arabidopsis cDNA library with the labeled OBF4 protein and isolated OBP1 (for OBF binding protein) [1].
  • Using protein-protein interaction screening with OBF4 we have isolated AtEBP, an Arabidopsis protein that contains a novel DNA-binding domain, the AP2/EREBP domain [2].
  • TGA3 was also found to be expressed at the same level throughout the plant, whereas genes encoding TGA1 and OBF4 have relatively high RNA expression levels in root [3].
 

Other interactions of TGA4

  • TGA5 acts as a positive and TGA4 acts as a negative regulator of ocs element activity in Arabidopsis roots in response to defence signals [4].
  • OBP1, an Arabidopsis Dof protein, was previously isolated through an interaction with OBF4, an ocs element-binding protein [5].

References

  1. Interactions between distinct types of DNA binding proteins enhance binding to ocs element promoter sequences. Zhang, B., Chen, W., Foley, R.C., Büttner, M., Singh, K.B. Plant Cell (1995) [Pubmed]
  2. Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein. Büttner, M., Singh, K.B. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  3. Binding specificity and tissue-specific expression pattern of the Arabidopsis bZIP transcription factor TGA2. de Pater, S., Pham, K., Memelink, J., Kijne, J. Mol. Gen. Genet. (1996) [Pubmed]
  4. TGA5 acts as a positive and TGA4 acts as a negative regulator of ocs element activity in Arabidopsis roots in response to defence signals. Foley, R.C., Singh, K.B. FEBS Lett. (2004) [Pubmed]
  5. Characterization of salicylic acid-responsive, arabidopsis Dof domain proteins: overexpression of OBP3 leads to growth defects. Kang, H.G., Singh, K.B. Plant J. (2000) [Pubmed]
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