Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Celsr2 - cadherin, EGF LAG seven-pass G-type...

Rattus norvegicus

Synonyms: Cadherin EGF LAG seven-pass G-type receptor 2, Megf3, Multiple EGF-like domains protein 3, Multiple epidermal growth factor-like domains protein 3

Shima, Y. et al., Beall, S.A. et al.

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High impact information on Celsr2

Celsr2 localized to the Golgi complex in Sertoli cells and germ cells [1].
Knocking down Celsr2 resulted in prominent simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, and this phenotype seemed to be due to branch retraction [2].

References

Hybrid GPCR/cadherin (Celsr) proteins in rat testis are expressed with cell type specificity and exhibit differential Sertoli cell-germ cell adhesion activity. Beall, S.A., Boekelheide, K., Johnson, K.J. J. Androl. (2005) [Pubmed]
Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin. Shima, Y., Kengaku, M., Hirano, T., Takeichi, M., Uemura, T. Dev. Cell (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CELSR2	Bos taurus
CELSR2	Canis lupus familiaris
CELSR2	Homo sapiens
Celsr2	Mus musculus
CELSR2	Pan troglodytes
celsr2	Xenopus (Silurana) tropicalis

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