Gene Review:
NIMIN1 - protein NIM1-INTERACTING 1
Arabidopsis thaliana
Synonyms:
NIM1-interacting 1, NIMIN-1, T6A9.23
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High impact information on NIMIN-1/NIMIN1
- These effects were dependent on the ability of NIMIN1 to interact with NPR1 [1].
- Interaction of NIMIN1 with NPR1 modulates PR gene expression in Arabidopsis [1].
- Mutant plants with a T-DNA insertion in NIMIN1 as well as transgenic plants with reduced NIMIN1 mRNA levels showed hyperactivation of PR-1 gene expression after SA treatment but no effect on the disease resistance phenotype [1].
Biological context of NIMIN-1/NIMIN1
- In an attempt to identify proteins involved in SA-mediated signal transduction, we previously described the isolation of three novel genes encoding distinct albeit structurally related proteins designated NIMIN1 (for NIM1-INTERACTING1), NIMIN2, and NIMIN3 that interact with NPR1 in the yeast two-hybrid system [1].
Other interactions of NIMIN-1/NIMIN1
- Our results strongly suggest that NIMIN1 negatively regulates distinct functions of NPR1, providing a mechanism to modulate specific features of SAR [1].
References
- Interaction of NIMIN1 with NPR1 modulates PR gene expression in Arabidopsis. Weigel, R.R., Pfitzner, U.M., Gatz, C. Plant Cell (2005) [Pubmed]
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