The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

SEP3  -  MADs box transcription factor SEPALLATA3

Arabidopsis thaliana

Synonyms: AGAMOUS-like 9, AGL9, F3I6.19, F3I6_19, SEPALLATA3, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on SEP3


Biological context of SEP3

  • However, comparing the phenotypes obtained by ectopic expression of STK and/or SHP1 with or without SEP3 shows that co-expression of factors that are able to form complexes in yeast cause more extreme homeotic transformations, confirming the functional role of these complexes in vivo [5].
  • Conserved hydrophobic positions are most important for the strength of both PI/AP3 and PI/SEP3 dimerization, though ionic and/or polar interactions appear to play a secondary role [6].

Physical interactions of SEP3

  • Taken together, these studies suggest that SEP3 interacts with AP1 to promote normal flower development [7].

Regulatory relationships of SEP3

  • Furthermore, the early flowering phenotype of plants constitutively expressing AP1 is significantly enhanced by constitutive SEP3 expression [7].

Other interactions of SEP3

  • Two AGL2-like MADS-box genes, Lily MADS Box Gene (LMADS) 3 and LMADS4, with extensive homology of LMADS3 to the Arabidopsis SEPALLATA3 were characterized from the lily (Lilium longiflorum) [8].

Analytical, diagnostic and therapeutic context of SEP3


  1. The flowering integrator FT regulates SEPALLATA3 and FRUITFULL accumulation in Arabidopsis leaves. Teper-Bamnolker, P., Samach, A. Plant Cell (2005) [Pubmed]
  2. APETALA1 and SEPALLATA3 interact with SEUSS to mediate transcription repression during flower development. Sridhar, V.V., Surendrarao, A., Liu, Z. Development (2006) [Pubmed]
  3. A new role of the Arabidopsis SEPALLATA3 gene revealed by its constitutive expression. Castillejo, C., Romera-Branchat, M., Pelaz, S. Plant J. (2005) [Pubmed]
  4. Identification and characterization of four chrysanthemum MADS-box genes, belonging to the APETALA1/FRUITFULL and SEPALLATA3 subfamilies. Shchennikova, A.V., Shulga, O.A., Immink, R., Skryabin, K.G., Angenent, G.C. Plant Physiol. (2004) [Pubmed]
  5. Functional analysis of MADS-box genes controlling ovule development in Arabidopsis using the ethanol-inducible alc gene-expression system. Battaglia, R., Brambilla, V., Colombo, L., Stuitje, A.R., Kater, M.M. Mech. Dev. (2006) [Pubmed]
  6. Defining subdomains of the K domain important for protein-protein interactions of plant MADS proteins. Yang, Y., Jack, T. Plant Mol. Biol. (2004) [Pubmed]
  7. APETALA1 and SEPALLATA3 interact to promote flower development. Pelaz, S., Gustafson-Brown, C., Kohalmi, S.E., Crosby, W.L., Yanofsky, M.F. Plant J. (2001) [Pubmed]
  8. Two lily SEPALLATA-like genes cause different effects on floral formation and floral transition in Arabidopsis. Tzeng, T.Y., Hsiao, C.C., Chi, P.J., Yang, C.H. Plant Physiol. (2003) [Pubmed]
  9. Mutant analysis, protein-protein interactions and subcellular localization of the Arabidopsis B sister (ABS) protein. Kaufmann, K., Anfang, N., Saedler, H., Theissen, G. Mol. Genet. Genomics (2005) [Pubmed]
WikiGenes - Universities