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Gene Review

SEU  -  SEUSS transcriptional co-regulator

Arabidopsis thaliana

Synonyms: F28H19.10, F28H19_10, seuss
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High impact information on SEU

  • Our data suggest that MADS box proteins are involved in the recruitment of the SEU-LUG repressor complex for the regulation of AGAMOUS [1].
  • Despite the molecular isolation of LUG and SEU, the biochemical function of these two proteins remains uncharacterized, and the mechanism of AGAMOUS repression remains unknown [2].
  • APETALA1 and SEPALLATA3 interact with SEUSS to mediate transcription repression during flower development [3].
  • Collectively, these data suggest that SEU is a novel factor affecting auxin response [4].
  • A model is proposed in which SEU functions jointly with ETT in auxin response to promote floral organ patterning and growth [4].

Biological context of SEU

  • The observed phenotypes remarkably resembled the leunig (lug) and seuss (seu) mutants [1].
  • Using a map-based approach, we isolated the SEUSS gene and showed that it encodes a novel protein with at least two glutamine-rich domains and a highly conserved domain that shares sequence identity with the dimerization domain of the LIM-domain-binding transcription co-regulators in animals [5].
  • SEUSS, a member of a novel family of plant regulatory proteins, represses floral homeotic gene expression with LEUNIG [5].
  • Here we show that SEUSS and LEUNIG control blade cell number and vasculature development within the petal [6].
  • SEUSS and LEUNIG regulate cell proliferation, vascular development and organ polarity in Arabidopsis petals [6].

Regulatory relationships of SEU

  • SEU encodes a novel protein that is predicted to transcriptionally co-repress the AGAMOUS floral organ identity gene [4].

Analytical, diagnostic and therapeutic context of SEU


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