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Gene Review:

WEE1 - Wee1-like protein kinase

Arabidopsis thaliana

Synonyms: ATWEE1, F22D16.3, F22D16_3, WEE1 kinase homolog, WEE1-KINASE

Sorrell, D.A. et al., Shimotohno, A. et al.

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High impact information on WEE1

Here, we show that CDKD;2 forms a stable complex with cyclin H and is downregulated by the phosphorylation of the ATP-binding site by WEE1 kinase [1].
Here we describe the isolation, by reverse transcription polymerase chain reaction (RT-PCR), of a WEE1 cDNA (AtWEE1) in Arabidopsis thaliana (L.) Heynh [2].

Analytical, diagnostic and therapeutic context of WEE1

Semi-quantitative RT-PCR showed that AtWEE1 expression was confined to actively dividing regions of the plant [2].

References

Diverse phosphoregulatory mechanisms controlling cyclin-dependent kinase-activating kinases in Arabidopsis. Shimotohno, A., Ohno, R., Bisova, K., Sakaguchi, N., Huang, J., Koncz, C., Uchimiya, H., Umeda, M. Plant J. (2006) [Pubmed]
A WEE1 homologue from Arabidopsis thaliana. Sorrell, D.A., Marchbank, A., McMahon, K., Dickinson, J.R., Rogers, H.J., Francis, D. Planta (2002) [Pubmed]

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