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Gene Review

mMDH1  -  malate dehydrogenase 1

Arabidopsis thaliana

Synonyms: mitochondrial malate dehydrogenase 1
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High impact information on AT1G53240

  • We report a novel plastidic NAD-dependent malate dehydrogenase (EC 1. 1.1.37), which is not redox-regulated in contrast to its NADP-specific counterpart (EC [1].
  • Cold acclimation also resulted in an increase in the reduction state of the stroma, as indicated by an increased total activity and activation state of NADP-dependent malate dehydrogenase, and increased light-dependent activities of the major regulatory enzymes of the oxidative pentose-phosphate pathway [2].


  1. A novel, non-redox-regulated NAD-dependent malate dehydrogenase from chloroplasts of Arabidopsis thaliana L. Berkemeyer, M., Scheibe, R., Ocheretina, O. J. Biol. Chem. (1998) [Pubmed]
  2. Cold acclimation of Arabidopsis thaliana results in incomplete recovery of photosynthetic capacity, associated with an increased reduction of the chloroplast stroma. Savitch, L.V., Barker-Astrom, J., Ivanov, A.G., Hurry, V., Oquist, G., Huner, N.P., Gardeström, P. Planta (2001) [Pubmed]
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