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Gene Review

EGL3  -  transcription factor EGL1

Arabidopsis thaliana

Synonyms: ATMYC-2, AtEGL3, EGL1, ENHANCER OF GLABRA 3, F24D7.16, ...
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High impact information on EGL3

  • These results suggest that GL3/EGL3 accumulation in the N cells is dependent on specification of the hair cell fate, which itself is known to be influenced (via CPC-mediated lateral inhibition) by the non-hair cells [1].
  • A network of putative transcriptional regulators, including the related bHLH proteins GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3), is known to influence the patterning of these cell types [1].
  • When mutated, egl3 gives totally glabrous plants only in the gl3 mutant background [2].
  • The double bHLH mutant, gl3 egl3, has a pleiotropic phenotype like ttg1 having defective anthocyanin production, seed coat mucilage production, and position-dependent root hair spacing [2].

Biological context of EGL3

  • A novel unlinked bHLH-encoding locus is described here, ENHANCER OF GLABRA3 (EGL3) [2].
  • Although they are thought to act in both the hair and non-hair cell types, we surprisingly found that GL3 and EGL3 gene expression and RNA accumulation occurs preferentially in the developing hair cells [1].
  • Two Arabidopsis bHLH genes, GLABRA3 (GL3) and MYC-146, encode proteins that are similar throughout the predicted amino acid sequence to R and DELILA, which regulate anthocyanin production in maize and snapdragon, respectively [3].

Analytical, diagnostic and therapeutic context of EGL3


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