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Gene Review:

Rab9a - RAB9A, member RAS oncogene family

Rattus norvegicus

Synonyms: Rab9, Ras-related protein Rab-9A

Soldati, T. et al., Soldati, T. et al.

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High impact information on Rab9

Here we describe the reconstitution of the selective targeting of prenylated Rab9 protein onto late endosome membranes and show that this process is accompanied by endosome-triggered nucleotide exchange [1].
Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP dissociation inhibitor complexes and endosome-enriched membranes [2].

Associations of Rab9 with chemical compounds

Rab9 is localized primarily to late endosomes, where it aids the transport of mannose 6-phosphate receptors to the trans-Golgi network [1].

References

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange. Soldati, T., Shapiro, A.D., Svejstrup, A.B., Pfeffer, S.R. Nature (1994) [Pubmed]
Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP dissociation inhibitor complexes and endosome-enriched membranes. Soldati, T., Shapiro, A.D., Pfeffer, S.R. Meth. Enzymol. (1995) [Pubmed]

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RAB9A	Bos taurus
RAB9A	Canis lupus familiaris
rab9a	Danio rerio
RAB9A	Gallus gallus
RAB9A	Homo sapiens
RAB9A	Macaca mulatta
Rab9	Mus musculus
RAB9A	Pan troglodytes
rab9a	Xenopus (Silurana) tropicalis

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