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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RTN4IP1  -  reticulon 4 interacting protein 1

Homo sapiens

Synonyms: NIMP, NOGO-interacting mitochondrial protein, Reticulon-4-interacting protein 1, mitochondrial
 
 
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Disease relevance of RTN4IP1

  • The anti-carbohydrate monoclonal antibody NIMP/M45 significantly enhanced granuloma formation [1].
 

High impact information on RTN4IP1

  • Within the CNS, NIMP-like immunoreactivity is present in neurons and astrocytes [2].
  • We identified a novel mitochondrial protein designated Nogo-interacting mitochondrial protein (NIMP) in a screen of an adult human brain cDNA library [2].
  • The mitochondrial localization of NIMP was evidenced by confocal image analysis and western blot analysis of isolated mitochondria [2].

References

  1. Dissociation of antibody responses during human schistosomiasis and evidence for enhancement of granuloma size by anti-carbohydrate IgM. Simpson, A.J., Yi, X.Y., Lillywhite, J., Ali, P.O., Kelly, C.G., Mott, R., Smithers, S.R., Oliveira, R.C., Katz, N., Rumjanek, F. Trans. R. Soc. Trop. Med. Hyg. (1990) [Pubmed]
  2. Identification and characterization of a novel Nogo-interacting mitochondrial protein (NIMP). Hu, W.H., Hausmann, O.N., Yan, M.S., Walters, W.M., Wong, P.K., Bethea, J.R. J. Neurochem. (2002) [Pubmed]
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