The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia
  • UniProt

Table of contents

About

Terms

 

Gene Review: 

GSY1  -  glycogen (starch) synthase GSY1

Saccharomyces cerevisiae S288c

Synonyms: YFR015C
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on GSY1

  • Expression of GSY1 was dependent upon the presence of a TATA box and two stress response elements (STREs) [1].
  • GSY1 resides on chromosome VI, and GSY2 is located on chromosome XII [2].
  • The amino-terminal sequence obtained from the 85,000-dalton species matched the NH2 terminus predicted by the GSY1 sequence [3].
  • Disruption of the GSY1 gene resulted in a viable haploid with glycogen synthase activity, and purification of glycogen synthase from this mutant strain resulted in an enzyme that contained the 77,000-dalton polypeptide [3].
  • The data are explained if S. cerevisiae has two glycogen synthase genes encoding proteins with significant sequence similarity The protein sequence predicted by the GSY1 gene lacks the extreme NH2-terminal phosphorylation sites of the mammalian enzymes [3].

References

  1. Multiple positive and negative elements involved in the regulation of expression of GSY1 in Saccharomyces cerevisiae. Unnikrishnan, I., Miller, S., Meinke, M., LaPorte, D.C. J. Biol. Chem. (2003) [Pubmed]
  2. Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled. Farkas, I., Hardy, T.A., Goebl, M.G., Roach, P.J. J. Biol. Chem. (1991) [Pubmed]
  3. Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene. Farkas, I., Hardy, T.A., DePaoli-Roach, A.A., Roach, P.J. J. Biol. Chem. (1990) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities