Gene Review:
TIM22 - Tim22p
Saccharomyces cerevisiae S288c
Synonyms:
D0884, Mitochondrial import inner membrane translocase subunit TIM22, YDL217C
- Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Sirrenberg, C., Bauer, M.F., Guiard, B., Neupert, W., Brunner, M. Nature (1996)
- Import of mitochondrial carriers mediated by essential proteins of the intermembrane space. Koehler, C.M., Jarosch, E., Tokatlidis, K., Schmid, K., Schweyen, R.J., Schatz, G. Science (1998)
- The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier. Curran, S.P., Leuenberger, D., Oppliger, W., Koehler, C.M. EMBO J. (2002)
- Biogenesis of Tim23 and Tim17, integral components of the TIM machinery for matrix-targeted preproteins. Káldi, K., Bauer, M.F., Sirrenberg, C., Neupert, W., Brunner, M. EMBO J. (1998)
- The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. Kerscher, O., Holder, J., Srinivasan, M., Leung, R.S., Jensen, R.E. J. Cell Biol. (1997)
- Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane. Koehler, C.M., Murphy, M.P., Bally, N.A., Leuenberger, D., Oppliger, W., Dolfini, L., Junne, T., Schatz, G., Or, E. Mol. Cell. Biol. (2000)
- The dynamic dimerization of the yeast ADP/ATP carrier in the inner mitochondrial membrane is affected by conserved cysteine residues. Dyall, S.D., Agius, S.C., De Marcos Lousa, C., Trezeguet, V., Tokatlidis, K. J. Biol. Chem. (2003)
- A cryptic matrix targeting signal of the yeast ADP/ATP carrier normally inserted by the TIM22 complex is recognized by the TIM23 machinery. Vergnolle, M.A., Sawney, H., Junne, T., Dolfini, L., Tokatlidis, K. Biochem. J. (2005)
- The essential function of the small Tim proteins in the TIM22 import pathway does not depend on formation of the soluble 70-kilodalton complex. Murphy, M.P., Leuenberger, D., Curran, S.P., Oppliger, W., Koehler, C.M. Mol. Cell. Biol. (2001)
- Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Kurz, M., Martin, H., Rassow, J., Pfanner, N., Ryan, M.T. Mol. Biol. Cell (1999)